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In this recent ICFO study, scientists have optically levitated nanoparticles in high vacuum conditions and measured the highest Q-factor ever observed in nano- or micromechanical systems. The combination of an ultra-high Q-factor together with the tiny mass of the nanoparticles leads to an unprecedented force sensitivity at room temperature. The system is so sensitive that the weak forces arising from collisions between the nanoparticle and the residual air molecules are enough to drive it into the nonlinear regime. For the first time, this study demonstrates that ultra-high Q-factor nano-resonators intrinsically behave nonlinearly. In addition, the researchers show that, when combined with feedback cooling, the levitating nanoparticle can be used as a force-sensor, sufficiently sensitive to detect ultra-weak interactions, such as non-Newtonian gravity-like forces and tiny forces arising from quantum vacuum fluctuations.